上QQ阅读APP看书，第一时间看更新
参考文献
1. Anastasiadis K，Fragoulakis V，Antonitsis P，et al.Coronary artery bypass grafting with minimal versus conventional extracorporeal circulation；an economic analysis.Int J Cardiol，2013，168（6）：5336-5343.
2. Szwed K，Bieliński M，Drozdz W，et al.Cognitive dysfunction after cardiac surgery.Psychiatr Pol，2012，46（3）：473-482.
3. Gaynor JW，Jarvik GP，Gerdes M，et al.Postoperative electroencephalographic seizures are associated with deficits in executive function and social behaviors at 4 years of age following cardiac surgery in infancy. J Thorac Cardiovasc Surg，2013，146（1）：132-137.
4. Stewart A，Katznelson R，Kraeva N，et al.Genetic variation and cognitive dysfunction one year after cardiac surgery.Anaesthesia，2013，68（6）：571-575.
5. Camera E，Mastrofrancesco A，Fabbri C，et al.Astaxanthin， canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stressresponsive enzymes.Exp Dermatol，2009，18（3）：222-231.
6. Wolf AM，Asoh S，Hiranuma H，et al. Astaxanthin protects mitochondrial redox state and functional integrity against oxidative stress.J Nutr Biochem，2010，21（5）：381-389.
7. Shen H，Kuo CH，Chou J，et al.Astaxanthin reduces ischemic brain injury in adult rats. FASEB J，2009，23（6）：1958-1968.
8.施乙飞，韩建阁，王准，等，不同麻醉下非体外循环冠状动脉旁路移植术患者术后早期认知功能比较.中华麻醉学杂志，2008，28（12）：1124-1125.
9.王准，韩建阁，施乙飞，等，非体外循环和体外循环下冠状动脉旁路移植术患者术后认知功能比较.中华麻醉学杂志，2009，29（1）：86-87.
10.寇党培，王准，韩建阁，等，右美托咪定对非体外循环冠状动脉旁路移植术患者心肌损伤的影响.中华麻醉学杂志，2011，31（5）：550-552.
11.王准，边卫，韩建阁，等，右美托咪定对体外循环心内直视手术患者脑氧代谢和糖代谢的影响.中华麻醉学杂志，2011，31（11）：1293-1295.
12. Buvanendran A，Kroin JS，Berger RA，et al.Upregulation of prostaglandin E2 andinterleukins in the central nervous system and peripheral tissue duringand after surgery in humans.Anesthesiology，2006，104（3）：403-410.
13. Kalman J，Bogats G，Babik B，et al.Elevated levels of inflammatory biomarkers in the cerebrospi-nal fluid after coronary artery bypass surgery are predictors of cognitivedecline.Neurochem Intern，2006，48（3）：177-180.
14. Wan Y，Xu J，Ma D，et al.Postoperative impair-ment of cognitive function in rats：A possible role for cytokine-mediated inflammation in the hippocampus.Anesthesiology，2007，106 （3）：436-443.
15. Formica F，Mariani S，Broccolo F，et al.Systemic and myocardial inflammatory response in coronary artery bypass graft surgery with miniaturized extracorporeal circulation：differences with a standard circuit and off-pump technique in a randomized clinical trial.ASAIO J，2013，59（6）：600-606.
16. Hsu WH，Lee BH，Pan TM，et al.Monascin attenuates oxidative stress-mediated lung inflammation via peroxisome proliferator-activated receptor-gamma（PPAR-γ）and nuclear factor-erythroid 2 related factor 2（Nrf-2）modulation. J Agric Food Chem，2014，62（23）：5337-5344.
17. Yoon SR，Yang SH，Suh JW，et al.Fermentation of smilax china root by Aspergillus usami and Saccharomyces cerevisiae promoted concentration of resveratrol and oxyresveratrol and the free-radical scavenging activity.J Sci Food Agric，2014，94（9）：1822-1826.
18. Kwon DH，Kim BS，Chang H，et al. Exercise ameliorates cognition impairment due to restraint stress-induced oxidative insult and reduced BDNF level.Biochem Biophys Res Commun，2013，434（2）：245-251.
19.刘超，闵苏，魏珂，等.兴奋性氨基酸受体拮抗剂减轻电休克诱发的大鼠学习记忆障碍和Tau蛋白的过度磷酸化.生理学报，2012，64（4）：387-402.
20.刘超，闵苏，魏珂，等.电休克干预对嗅球切除抑郁模型大鼠海马Glu浓度和Tau蛋白过度磷酸化的影响.中国医学科学院学报，2012，34（3）：216-221.
21.刘旭阳，张清炯.眼病的细胞和分子生物学基础.北京：科学出版社，2010：337.
22. Kanamori A，Catrinescu MM，Mahammed A，et al.Neuroprotection against superoxide anion radical by metallocorroles in cellular and murine models of optic neuropathy.J Neurochem，2010，144（2）：488-498.
23. Guemez-Gamboa A，Estrada-Sánchez AM，Montiel T，et al. Activation of NOX2 by the stimulation of ionotropic and metabotropic glutamate receptors contributes to glutamate neurotoxicity in vivo through the production of reactive oxygen species and calpain activation.J Neuropathol Exp Neurol，2011，70（11）：1020-1035.
24. Dou W，Palomero-Gallagher N，van Tol MJ，et al.Systematic regional variations of GABA，glutamine，and glutamate concentrations follow receptor fingerprints of human cingulate cortex.J Neurosci，2013，33（31）：12698-12704.
25. Xing Y，Jiang H，He Y，et al.Effects of insulin-like growth factor-1 on neurochemical phenotypes of cultured dorsal root ganglion neurons with excitotoxicity induced by glutamate.Pharmazie，2013，68（1）：63-68.
26. Yokota H，Narayanan SP，Zhang W，et al.Neuroprotection from retinal ischemia/reperfusion injury by NOX2 NADPH oxidase deletion.Invest Ophthalmol Vis Sci，2011，52（11）：8123-8131.
27. Züngün C，Yilmaz FM，Tutkun E，et al.Assessment of serum S100B and neuron specific enolase levels to evaluate the neurotoxɪc effects of organɪc solvent exposure.Clin Toxicol （Phila），2013，51（8）：748-751.
28. Oktay Tureli H，Ungan I，Tureli D，et al.Risk of cerebral embolism after interventional closure of symptomatic patent foramen ovale or atrial septal defect：a diffusion-weighted MRI and neuron-specific enolase-based study. J Invasive Cardiol，2013，25（10）：519-524.
29. Zhai J，Cheng L，Dong J，et al.S100B gene polymorphisms predict prefrontal spatial function in both schizophrenia patients and healthy individuals. Schizophr Res，2012，134 （1）：89-94.
30. Bayram H，Hidiroglu M，Cetin L，et al.Comparing S-100 beta protein levels and neurocognitive functions between patients undergoing on-pump and off-pump coronary artery bypass grafting.J Surg Res，2013，182（2）：198-202.
31. Li YC，Xi CH，An YF，et al.Perioperative inflammatory response and protein S-100β concentrations-relationship with post-operative cognitive dysfunction in elderly patients.Acta Anaesthesiol Scand，2012，56（5）：595-600.
32.刘超，张雪宁，刘东，等.异丙酚、人参皂苷Rg-1、蛋白磷酸酯酶-2A和氯化锂对大鼠电休克后学习记忆以及海马内谷氨酸含量的影响.中国医学科学院学报，2014，36 （3）：234-240.
33.刘超，闵苏，魏珂，等.2，6-二异丙基苯酚、人参皂苷Rg-1和氯化锂逆转电休克后嗅球切除抑郁大鼠学习记忆障碍.中国药理学通报，2012，28（8）：1125-1130.
34. Weingarten MD，Lockwood AH，Hwo SY，et al. A protein factor essential for microtubule assembly. Proc Natl Acad Sci USA，1975，72（5）：1858-1862.
35. Osiecka KM，Nieznanska H，Skowronek KJ，et al.Tau inhibits tubulin oligomerization induced by prion protein.Biochim Biophys Acta，2010，1813（10）：1845-1853.
36. De Calignon A，Fox LM，Pitstick R，et al.Caspase activation precedes and leads to tangles. Nature，2010，464（16）：1201-1204.
37. Combs B，Voss K，Gamblin TC.Pseudohyperphosphorylation has differential effects on polymerization and function of tau isoforms.Biochemistry，2011，50（44）：9446-9456.
38. Akoury E，Gajda M，Pickhardt M，et al.Inhibition of tau filament formation by conformational modulation.J Am Chem Soc，2013，135（7）：2853-2862.
39. Canu N，Filesi I，Pristerà A，et al.Altered intracellular distribution of PrPC and impairment of proteasome activity in Tau overexpressing cortical neurons. J Alzheimers Dis，2011，27（3）：603-613.
40. Kopeikina KJ，Carlson GA，Pitstick R，et al.Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer’s disease brain.Am J Pathol，2011，179（4）：2071-2082.
41. Amadoro G1，Corsetti V，Atlante A，et al. Interaction between NH（2）-tau fragment and Aβ in Alzheimer’s disease mitochondria contributes to the synaptic deterioration.Neurobiol Aging，2012，33（4）：833.e1-25.
42. Liu SJ，Zhang AH，Li HL，et al.Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory.J Neurochem，2003，87 （6）：1333-1344.
43. Ma QL，Zuo X，Yang F，et al.Curcumin suppresses soluble tau dimers and corrects molecular chaperone，synaptic，and behavioral deficits in aged human tau transgenic mice.J Biol Chem，2013，288（6）：4056-4065.
44. De la Torre JC.Pathophysiology of neuronal energy crisis in Alzheimer’s disease. Neurodegener Dis，2008，5（3-4）：126-132.
45. Roberson ED，Scearce-Levie K，Palop JJ，et al. Reducing endogenous Tau ameliorates amyloid beta-induced deficits in an Alzheimer’s disease mouse model.Science，2007，316 （5825）：750-754.
46. Gasparini L，Crowther RA，Martin KR，et al.Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice：effects on axonal viability.Neurobiol Aging，2011，32 （3）：419-433.
47. Bull ND，Guidi A，Goedert M，et al.Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau.PLoS One，2012，7（4）：e34724.
48. Miller EC，Teravskis PJ，Dummer BW，et al.Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits. Eur J Neurosci，2014，39（7）：1214-1224.
49. Nassiri-Asl M，Naserpour Farivar T，Farivar TN，et al.Rutin activates the MAPK pathway and BDNF gene expression on beta-amyloid induced neurotoxicity in rats. Toxicol Lett，2014，224（1）：108-113.
50. Klinger RY，James OG，Wong TZ，et al.Cortical β-amyloid levels and neurocognitive performance after cardiac surgery. BMJ Open，2013，3（9）：e003669.
51. Akhter R，Sanphui P，Biswas SC，et al.The essential role of p53-up-regulated modulator of apoptosis（Puma）and its regulation by FoxO3a transcription factor in β-amyloid-induced neuron death.J Biol Chem，2014，289（15）：10812-10822.
52. Hsu MJ，Sheu JR，Lin CH，et al.Mitochondrial mechanisms in amyloid beta peptide-induced cerebrovascular degeneration.Biochim Biophys Acta，2010，1800（3）：290-296.
53.刘超，闵苏. Tau蛋白的研究进展.临床麻醉学杂志，2012，28（5）：105-107.
54.中华医学会神经病学分会痴呆与认知障碍学组写作组.血管性认知障碍诊治指南.中华神经科杂志，2011，44 （2）：142-147.
55.薛海波.阿尔茨海默病的神经心理学和神经化学诊断研究.上海交通大学，2006.
56. Roy CW，Sherrington CS.On the regulation of the bloodsupply of the brain.J Physiol，1890，11（1-2）：85-158，17.
57. Duan X，Zhang D，Nie L，et al.Rapid discrimination of geographical origin and evaluation of antioxidant activity of Salvia miltiorrhiza var.alba by Fourier transform near infrared spectroscopy. Spectrochim Acta A Mol Biomol Spectrosc，2013，122C：751-757.
58. Rohlfs-Domínguez P.Studying the effects of smell and taste experience in the pediatric population using functional near infrared spectroscopy：A hypothesis.Med Hypotheses，2014，82（1）：89-93.
59.史景发，洪四名，李元海.术中调控不同呼气末二氧化碳分压对老年腹腔镜手术患者术后认知功能的影响.临床麻醉学杂志，2013，29（10）：989-992.
60. Terada S，Sato S，Nagao S，et al.Trail making test B and brain perfusion imaging in mild cognitive impairment and mild Alzheimer’s disease.Psychiatry Res，2013，213（3）：249-255.
61. Sommer B，Grummich P，Hamer H，et al. Frameless stereotactic functional neuronavigation combined with intraoperative magnetic resonance imaging as a strategy in highly eloquent located tumors causing epilepsy.Stereotact Funct Neurosurg，2013，92（1）：59-67.
62. Ashare RL，Wileyto EP，Ruparel K，et al.Effects of tolcapone on working memory and brain activity in abstinent smokers：A proof-of-concept study. Drug Alcohol Depend，2013，133（3）：852-856.